教授（研究员）

【学术组织任职】重庆市生物化学与分子生物学学会理事，生物化学与分子生物学学会青年分会理事，食品学会会员；国家自然科学基金、重庆市科技局等国家和省部级项目评审专家。

1.天然活性物质的形成机制及对人体健康的功效：采用分子生物学、基因工程、组学等技术解析红曲霉等微生物、中草药等植物中对人体健康具有功效作用的活性成分及其合成调控机制。

2.功能性活性物质的绿色生物制造：采用合成生物学策略对活性物质生物合成通路进行重构和优化，实现高效生物合成和产业化应用。

3.基于活性物质的大健康产品开发：药品、特医食品、功能食品等。

1.国家重点研发计划子课题，维生素B6和人参皂苷Rg3/Rh2生物合成元件的挖掘和途径重构"（2022YFC2106201）

2. 国家自然科学基金面上项目，番茄EIN3-binding F-box蛋白2超表达诱导单性结实和果实成熟异常的机制研究

3. 重庆市科技计划项目基础科学与前沿技术面上项目，番茄SlIPT2基因在座果及果实发育过程中的生物学功能研究

4. 国家自然科学基金面上项目，番茄Sly-miR167及其靶基因SlARF6和SlARF8对座果、果实发育和成熟的调控研究

1. Qiujing Ao, Tiaoshuang Qiu, Feng Liao, Zichao Hu, Yingwu Yang*. Knockout of SlYTH2, encoding a YTH domain-containing protein, caused plant dwarfing, delayed fruit internal ripening, and increased seed abortion rate in tomato. Plant Sci. 2023,335:111807

2. Shuangqin Yin, Qiujing Ao, Tiaoshuang Qiu, Caiyun Tan, Yun Tu, Tianyin Kuang, Yingwu Yang*. Tomato SlYTH1 encoding a putative RNA m6A reader affects plant growth and fruit shape, Plant Sci. 2022, 323: 111417

3. Jieli Ji, Fen Chen, Shuai Liu, Yingwu Yang, Changjun Hou, Yongzhong Wang. Co-production of biogas and humic acid using rice straw and pig manure as substrates through solid-state anaerobic fermentation and subsequent aerobic composting. J Environ Manage. 2022,320: 115860

4. Shuangqin Yin, Qiujing Ao, Caiyun Tan, Yingwu Yang*. Genome‑wide identification and characterization of YTH domain‑containing genes, encoding the m6A readers, and their expression in tomato. Plant Cell Rep. 2021,40:1229-1245

5. Wenjing Cheng, Shuangqin Yin, Yun Tu, Hu Mei, Yongzhong Wang, Yingwu Yang*. SlCAND1, encoding cullin‑associated Nedd8‑dissociated protein 1, regulates plant height, flowering time, seed germination, and root architecture in tomato. Plant Mol Biol. 2020,102:537–551

6. Yong Zhang, Shuangqin Yin, Yun Tu, Hu Mei, Yingwu Yang*. A novel microRNA, SlymiR208, promotes leaf senescence via regulating cytokinin biosynthesis in tomato. Physiol Plantarum. 2020,169:143–155

7. Tingting Shi, Yingwu Yang*, Shuheng Huang, Linxin Chen, Zuyin Kuang, Yu Heng, Hu Mei*. Molecular image-based convolutional neural network for the prediction of ADMET properties. Chemometr Intell Lab. 2019,194:103853

8. Lei Zhang, Chunmei Liao, Yingwu Yang, Yong-Zhong Wang, Ke Ding, Danqun Huo. Response of lipid biosynthesis in Chlorella pyrenoidosa to intracellular reactive oxygen species level under stress conditions. Bioresource Technol. 2019,287:121414.

9. Xiaokun Guo, Yong Zhang, Yun Tu, Yongzhong Wang, Wenjing Cheng, Yingwu Yang*. Overexpression of an EIN3-binding F-box protein2-like gene caused elongated fruit shape and delayed fruit development and ripening in tomato. Plant Sci. 2018,272:131-141

10. Yong Zhang, Zhengguo Li, Yun Tu, Wenjing Cheng, Yingwu Yang*. Tomato (Solarium lycopersicum) SIIPT4, encoding an isopentenyltransferase, is involved in leaf senescence and lycopene biosynthesis during fruit ripening. BMC Plant Biol. 2018,18:107

1. 杨迎伍，李正国，吴玉，邓伟. 一种适用于microRNAs分析的番茄总RNA提取方法，2012.8，中国，ZL201010521015.4（已授权）

2. 杨迎伍，吴玉，李正国，邓伟. 外植体表面灭菌装置，2010.5，中国，ZL200920127575.4

3. 邓伟，李正国，杨迎伍，罗克明，金凯. 诱导胚状体形成和植物再生的植物双元表达载体及其构建方法和应用，2010.11，中国，ZL200810237002.7

生物医学工程：1.天然产物开发与利用； 2.合成生物学；3.途径工程

生物与医药：1. 生物医药工程与转化；2. 医药原料与制剂工程